In late December, 1924, 21-year-old Agnes Nazar, nee Fortquian, an immigrant from Persia (modern-day Iran), died at Chicago's St. Joseph's Hospital from an abortion performed earlier that day. In early January, 1925, Rogie Hatal was held by the coroner as the guilty abortionist. Hatal's profession is not listed.

St. Joseph's was originally founded as Providence Hospital in 1868 to care for victims of a cholera outbreak. Three nuns from the Daughters of Charity rented a two-story cottage for the purpose. In 1870, land was purchased for a new building, which was under construction during the Great Chicago fire. The new building was spared and was used as a shelter for fire victims. it officially opened as St. Joseph Hospital in 1872.

St. Joseph operated the first TB unit in Chicago and also opened the first psychiatry unit in the city. The hospital opened the Saint Joseph School of Nursing in 1893. This school graduated around 1,500 nurses before closing in 1964. By then the hospital was in a new location, where it had moved in 1961.

In 1995, St. Joseph merged with Columbus Hospital and Saint Anthony Hospital, forming Catholic Health Partners. Sponsorship is now under Resurrection Health Care.